BÁO CÁO Y HỌC: " EFFECTIVENESS OF ANTIRETROVIRAL THERAPY AND DEVELOPMENT OF DRUG RESISTANCE IN HIV-1 INFECTED PATIENTS IN MOMBASA, KENYA" DOC
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2International Centre for Reproductive Health, Mombasa, Kenya, 3Aids Reference Laboratory, Ghent University, Ghent, Belgium, 4Coast Provincial General Hospital, Mombasa, Kenya, 5Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya[r]
Little is known about the provision of care for HIV-infected children during complex emergencies. In a smallstudy from an area with long-standing conflict in Uganda,children on ART had high adherence and low mortal-ity.[10] However, there are few guidelines to dire[r]
Isaakidis et al. Journal of the International AIDS Society 2010, 13:11http://www.jiasociety.org/content/13/1/11Page 9 of 1020. Viani RM, Araneta MR, Deville JG, Spector SA: Decrease in hospitalizationand mortality rates among children with perinatally acquired HIV type
The cytidine deaminase CEM15 induces hypermutation innewly synthesized HIV-1 DNA. Nature 2003, 424:94-98.Abstract9. Salomon H, Wainberg M-A, Brenner B, et al.: Prevalence of HIV-1resistant to antiretroviral drugs in 81 individuals newlyinfected by sexual contact or[r]
25. Misumi S, Endo M, Inatsu A, Hashimoto K, Takamune N, Shoji S: HumanImmunodeficiency Virus-Induced Apoptosis of Human Breast CancerCells Via CXCR4 is Mediated by the Viral Envelope Protein But Does NotRequire CD4. Current HIV Research 2008, 6:34-42.26. Gaughan EM, Dezube BJ, Bower M, Aboul[r]
oside reverse transcriptase inhibitor (NRTI) substitutionswere made within regimen 1 or 2 for NRTI-associated tox-icities.Study proceduresAt the screening visit, HIV-positive individuals met withthe clinic nurse, who completed a demographic informa-tion sheet. Blood was drawn for viral load,[r]
navir plus zidovudine and lamivudine in the treatment ofHIV-1 infection in adults. N Engl J Med 1999, 341:1865-1873.Abstract34. Delaugerre C, Rohban R, Simon A, et al.: Resistance profile andcross-resistance of HIV-1 among patients faili[r]
who visited the HIV clinic. Since August 2003, we treated patients with HAART. Only basiclaboratory services were available.Results: We followed 185 patients in the pre-HAART cohort and 180 patients in the HAARTcohort. The mortality rate was 15.4 per 100 per[r]
3. Gender-related development index. Available at http://hdr.undp.org/en/media/HDR_20072008_GDI.pdf. 4. Trends in Maternal Mortality: 1990–2008: Estimates developed by WHO, UNICEF, UNFPA, and the World Bank 5. Kenya National Bureau of Statistics (KNBS) and I[r]
Design: The Prospective Study on the Use and Monitoring of Antiretroviral Therapy (PUMA) is astudy of 883 HIV-positive individuals enrolled in the Argentinean drug treatment program.Individuals were 16 years of age and older and w[r]
death and prediction of OLT-free survival. In a prospective study of indefinite LAM pre-OLT therapy, 32 of 154 patients (21%) died and 25 of the 32 deaths occurred within 6 months of initiating therapy [52]. Bilirubin, crea[r]
Because of the large number of prescribers, each with asmall number of patients, as well as frequently changingregimens, educational interventions aimed at hospitalphysicians are not practical. One potential solution ismandatory consultation with an ID/HIV specialist. Pre[r]
preparing the manuscript. MM participated in the designof the study. RA participated in the design of the study andpreparing the manuscript. All authors read and approvedthe final manuscript.References1. Dean GL, Edwards SG, Ives NJ, Matthews G, Fox EF, Navaratne L[r]
-resistant tuberculosis (XDR-TB) which accounted for on average 10% of the detected MDR-TB case [45]. XDR-TB is TB that is resistant to at least isoniazid and rifampin among the first-line anti-TB drugs (which is the definition of MDR-TB), and in addition to that t[r]
risk events with resistant virus.The opportunity to follow a subset of the patients longitu-dinally has enabled us to document that HIV-positivepatients in this study had transitions over time in theirpredominant detectable viral genotype from 1-class to 2-class or[r]
therapy assessment variables using simple and weighted Kappa analysis.Results: Two hundred fifty-four patients were seen by a nurse and physician, while 267 were seenby a clinical officer and physician. The majority (> 50%) in each arm of the s[r]
Page 6 of 6(page number not for citation purposes)ponents of second-line regimens.[20] Failing of tNRTIsleads to accumulation of thymidine analog resistancemutations that can compromise the entire NRTI class.There are a few limitations in using this regimen as firs[r]
EDI T O R I A L Open AccessCreate a translational medicine knowledgerepository - Research downsizing, mergers andincreased outsourcing have reduced the depthof in-house translational medicine expertise andinstitutional memory at many pharmaceuticaland biotech companies: how will they avoidrel[r]
to the patients was the same as that used in the pilot study. Following a meal and after 19:00 on the day before surgery, the patients were given three bottles of the study solution (500 mL 3 bottles) and allowed to freely consume the solution until 2 h be[r]