BÁO CÁO KHOA HỌC:" THE INTERACTION BETWEEN THE MEASLES VIRUS NUCLEOPROTEIN AND THE INTERFERON REGULATOR FACTOR 3 RELIES ON A SPECIFIC CELLULAR ENVIRONMENT" PDF
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This work is dedicated to the memory of Bruno Curti. He was an excellent teacher and a brilliant scientist. He largely contributed to SL's decision to become a scientist.This work was supported by the CNRS, and by the Agence Nationale de la Recherche, specific[r]
were transfected with HA-CKIa, the lysates were then clarifiedbefore the addition of 10 lg of recombinant GST-14-3-3. Each sam-ple was rotated at 4 °C for 1 h before the addition of glutathionebeads. After 2 h, each pull-down was washed three times in lysisbuffer be[r]
during muscle ischemia [25,45] or after a calpain treatment ofisolated myofibrils [25]. Targeting of Z-disk by calpains waspreviously suggested [25,44,48] and a quick ask release frommuscles treated by calpains in the presence of calcium wasobserved. Furthermore, a-actinin is also locat[r]
through recognition of ISRE sequences. Thus, IRF-3was considered as a potential candidate to regulateISGs in the early events of innate response to virusinfection. In a previous study, we used a constitutivelyactive form of IRF-3 (IRF-3 5D) to stimulate tran-scription of[r]
optimized by molecular mechanical modeling and at the AM1 level of the-ory for three model substrates (with H, a methoxy group or a nitro groupin the para position in the leaving group). Intrinsic interactions of severalfunctional groups at the active site o[r]
Fig. 6. Co mpar ison of Model III (curve i) and Model IV (curve ii)simulation results with experimental data for fractional protein expres-sion of wild-type for genes with one binding site (A) and genes with twobinding sites (B). Solid circles and solid triangles denote e xperim[r]
company’s ability to recruit and retain talented people. The behavioral factors inworkplace environment may be considered keys affecting employee’s performancewhich may include engagement, productivity, morale, comfort level, etc. It is acceptedthat better workplace environme[r]
MA, Dupont E, Goldman M, Stordeur P: A rapid test to monitoralloreactive responses in whole blood using real-timepolymerase chain reaction. Transplantation 2005, 80:410-413.17. Catalina MD, Sullivan JL, Bak KR, Luzuriaga K: Differential evolu-tion and stability of epitope-specific CD8([r]
VNU Journal of Science, Mathematics - Physics 24 (2008) 145-154Quantum kinetic equation in the quantum hadrondynamics(QHD-I) modelPhan Hong Lien*100 Hoang Quoc Viet Street, Hanoi, VietnamReceived 8 August 2008; received in revised form 30 August 2008Abstract. Within the framework of
microbial noncytotoxic RNases, represented by RNases T1and U2. This similarity involves the three catalytic residuesand also the Arg121 residue, whose counterpart in RNaseT1, Arg77, is located in the vicinity of the substrate phos-phate moiety although its potential funct[r]
Pex1p and Pex6p on the same blot.AAA complex and peroxisomal importomer K. Rosenkranz et al.3806 FEBS Journal 273 (2006) 3804–3815 ª 2006 The Authors Journal compilation ª 2006 FEBSinteraction of the membrane-bound AAA complex andthe importomer. Therefore, the[r]
Keywords: a poptosis; IFN-c;IRF-1;TRAIL.Apoptosis is a n active cell death proc ess that i s geneticallyregulated. This process plays an important role in thedevelopment and homeostasis of multicellular organisms[1]. Among apoptosis-inducing proteins, the best character-ized are the[r]
Cubism was one of the strongest art movements in the 20th century that gave birth to many othermovements such as futurism and suprematism. The Forefathers of this revolutionary way ofpainting were Pablo Picasso and George Braque. Although it may have seemed to be a[r]
Y. Le et al. Functional domains in FPRL1FEBS Journal 272 (2005) 769–778 ª 2005 FEBS 771found in the seventh TM and the proximal half of thecytoplasmic tail connecting the seventh TM (Fig. 1).Thus, the sixth TM domain and the third extracellularloop of[r]
these experiments clearly demonstrate that neither exogen-ously expressed nor native Ruk L isoform is degraded viaproteasome or lysosome pathways.DISCUSSIONUbiquitination is now recognized as a regulatory proteinmodification whose functional significance is comparable tothat of phosphorylation. Degrad[r]
ter of the interface, and not from the accumulation ofnumerous weak contacts [30,31]. It showed that theenergetic effects of the individual mutations were notindependent, and suggested that some mutations resul-ted in local conformational changes. The assess[r]