BÁO CÁO Y HỌC: " EFFECTOR MECHANISMS OF INTERLEUKIN-17 IN COLLAGEN-INDUCED ARTHRITIS IN THE ABSENCE OF INTERFERON-Γ AND COUNTERACTION BY INTERFERON-Γ" POT
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the exact prevalence of which is unknown. Int. J. Med. Sci. 2006, 3 37Chronic hepatitis C In patients with clinical or biological signs of chronic liver disease, chronic hepatitis C is certain when both anti-HCV antibodies and HCV RNA (sought for with a sensitive technique, detecting 50 IU/ml or les[r]
cirrhosis.[51-53] Once decompensated cirrhosis occurs, the 5-year survival rate falls to 50%.[51] The time from HCV infection to cirrhosis is dependent on multiple factors, and cannot be predicted in an individual patient. Virtually all HCV-related HCC occurs among patients with cirrhosis. In a meta[r]
report was similar to a similar protocol used in 1995 by the same principal investigator. [13] Of the 20 patients who were given interferon alfa-2b, 5MU/day subcutaneously, 60% cleared virus on therapy and 20% had SVR. Of those that cleared virus, 33% remained non-viremic after liver transplantation[r]
ethanol-induced apoptosis when applied at low concentration, as confirmed by completely suppressing apoptosis after caspase-8 inhibition [12]. Fas receptor activation has been involved not only with the apoptotic process, but also with triggering of other intracellular signaling pathways [15, 16]. T[r]
acute HCV infection persists and 4% to 20% of patients with chronic hepatitis C will develop liver cirrhosis within 20 years. In patients with liver cirrhosis, the risk to develop HCC is 1-5% per year. Current standard therapy is the combination of pegylated interferon-α (PEG-IFN-α) and ribavirin. D[r]
report was similar to a similar protocol used in 1995 by the same principal investigator. [13] Of the 20 patients who were given interferon alfa-2b, 5MU/day subcutaneously, 60% cleared virus on therapy and 20% had SVR. Of those that cleared virus, 33% remained non-viremic after liver transplantation[r]
antibiotic resistance on the eradication rate of Helicobacter pylori infection by a 1-week regimen of proton pump inhibitor, amoxicillin and clarithromycin. Aliment Pharmacol Ther. 2003; 17: 259-65. 17. Miki I, Aoyama N, Sakai T, et al. Impact of clarithromycin resistence and CYP2C19 g[r]
but is now recognized as an illness of insulin resistance and resultant hyperinsulinemia. First line therapy now specifically targets insulin-mediated glucose utilization in the liver and peripheral tissue. [17-18] It has now been demonstrated that improvement occurs in both steatosis and the[r]
The aim of this study was to characterize global changes of apoptosis-related proteins induced by hypoxia in trophoblastic cells so as to clarify the mechanism of hypoxia-induced apoptos[r]
tent (50%of total daily caloric intake) in the diet re-sulted in sustained losses in weight and body fat [17]. The favorable effects on body composition in this study appear to be due to sustained decrease in appe-tite and ad libitum caloric intake induced by the high-protein intake. More rec[r]
what appears to be a relatively weak, ineffective immune response since it is inadequate to clear the virus. Since immunologic mediated inflammation is thought to be the mechanism of progressive fibrosis, it is surprising that immune suppression does not ameliorate the disease at the expense of high[r]
In the present study, two different sets of experiments were designed and performed. In the first, rat BMP6 cDNA from adult Sprague–Dawley (SD) rats was cloned and sequenced. A recombinant first-generation adenovirus ADrBMP6 was constructed and compared with ADhBMP6 in the process of bone formation.[r]
C. Persistence of hepatitis B and hepatitis C viral genomes in primary liver cancers from HBsAg-negative patients: a study of a low-endemic area. Hepatology 1993;17:20-29. 33. Koike K, Kobayashi M, Gondo M, Hayashi I, Osuga T, Takada S. Hepatitis B virus DNA is frequently found in liver biops[r]
SYBR green RT-PCR kit (Qiagen, Hilden, Germany). Gene expression 16 weeks after the intervention was evaluated against baseline. For normalization the housekeeping gene GADPH was applied as a reference gene. The primers for GADPH were: (forward) 5’-CAA GGT CAT CCC TGA CGT GAA-3’ and (reverse) 5’-CAG[r]
association between maternal use of loratadine in early pregnancy and birth of infants with hypospadias was the result of multiple testing. Acknowledgments The study was supported by a grant from K A Wallenberg Foundation, Sweden, to BK. Conflict of interest The authors have declared that no conflic[r]
of general populations [8, 9], and as high as 30% of the population aged 65 and older in the Framingham Heart Study (tHcy > 14 nmol/ml) [10]. Increasing tHcy concentrations accelerate cardiovascular diseases by promoting vascular inflammation, endothelial dys-function, and hypercoagulability[r]
mortality in women. Familial breast cancer is a small subset of this disease contributing to about 5 to 10% of breast cancer cases. Germline mutations of the breast tumor suppressor genes BRCA1 and BRCA2 have been found to contribute to most of the familial breast cancer cases [1-5]. BRCA1 was mappe[r]
associated with a higher risk of type 2 DM [17]. To our knowledge there are no other reports of a direct link between poultry consumption and risk of diabetes or of interactions between poultry consumption and BMI and the risk of type 2 DM. Red meat consumption was associated with a modest in[r]