BÁO CÁO Y HỌC: "MESENCHYMAL STEM CELLS IN ARTHRITIC DISEASE" POT

effect on local tissue repair through modulating localenvironment and activation of endogenous progenitor cells.These features make MSC-based cell therapy a hotly pursuedsubject of investigation in regenerative medicine.1. Biology of mesenchymal stem cellsCharacteristics[r]

Hội nghị phối hợp HUGO Pacirc (Human Genome Organisation) lần thứ 4 và ASIA Pacirc lần thứ 5 về Gen Học Ngời tại Bangkok Thái Lan GS Vũ Triệu An* Bộ môn Miễn dịch sinh lý bệnh - Trờng Đại học Y Hà Nội Không phải là ngời đợc trực tiếp đi dự Hội nghị nhng nhờ Tiến sĩ Đỗ Năng Vinh có tham gia đã đem v[r]

tumor suppressor genes wo uld lead to prostatecarcinogenesis.Additionally, Barker et al [72] and Zhu et al [43] dis-covered crypt stem cells as the origin of intestinal can-cer. They demonstrated that Lgr5 positive or prominin1positive subpopulations were intesti nal stem cel[r]

group 3 than in group 1 (Table 1). On the other hand,the mRNA expressions of endothelial nitric oxidesynthase (eNOS), IL-10, adiponectin, the anti-inflamma-tory indexes, were notably lower in group 2 than ingroup 3 (Table 1). These findings imply that ADMSCtherapy inhibited inflammator[r]

The authors declare that they have no competing interests.Received: 10 January 2011 Accepted: 5 May 2011 Published: 5 May 2011References1. Parikh CR, Coca SG, Wang Y, Masoudi FA, Krumholz HM: Long-termprognosis of acute kidney injury after acute myocardial infarction. ArchIntern Med 2008, 168:987-99[r]

ment, e mbolization, survival in the circulation, arrest,extravasation, evasion of the host defense and progres-sive growth [91]. Given its comp licated nature, metasta-sis is far from being understood completely and manyhypotheses have been proposed to elucidate the underly-ing mechanisms. <[r]

Chapter 067. Applications of Stem Cell Biology in Clinical Medicine (Part 2) Strategies for Stem Cell Replacement Stem cell transplantation is not a new concept and it is already part of established medical practice. Hematopoietic stem cells (HSCs) (Chap. 6[r]

large spherical cell body and short processes. During postnatal stages of development,the ameboid microglia transform into ramified microglia with several long processes.Upon activation by inflammatory stimuli, the ramified microglia undergo a series ofmorphological and functional changes in[r]

II 1–3 1 1 III 1–3 2–3 2–3 IV 2–4 2–4 2–4 One general approach to the prevention of GVHD is the administration of immunosuppressive drugs early after transplant. Combinations of methotrexate and either cyclosporine or tacrolimus are among the most effective and widely used regimens. Prednisone, ant[r]

collected in most circumstances, leads to rapid and sustained engraftment in virtually all cases. Compared to the use of autologous marrow, use of peripheral blood stem cells results in more rapid hematopoietic recovery, with granulocytes recovering to 500/µL by da[r]

Adult mesenchymal stem cells (MSCs) are typicallydefined as undifferentiated multipotent cells endowedwith the capacity for self-renewal and the potential to dif-ferentiate into several distinct cell lineages [1]. These pro-genitor cells which constitute a reservoi[r]

bone marrow–derived stem cells transplanted into heart, liver, and other organs suggested that the cells had differentiated into organ-specific cell types. Subsequent studies, however, revealed that the stem cells had fused with cells resident in the[r]

David F Stroncek (2006), Pancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation, Journal of Translational Medicine, doi: 10.1186/1479-5876-5-1. 39. Jiyeon Lee, Duck-Jong Han, Song-Che[r]

bone formation by marrow-derived endothelial and osteogenic cell transplantation. J Biomed Mater Res A, 92A (1): 246-253. Kim, S.; Von Recum, H. (2008) Endothelial stem cells and precursors for tissue engineering: Cell source, differentiation, selection, and application. Tissue Eng B,[r]

David F Stroncek (2006), Pancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation, Journal of Translational Medicine, doi: 10.1186/1479-5876-5-1. 39. Jiyeon Lee, Duck-Jong Han, Song-Che[r]

David F Stroncek (2006), Pancreatic islet cell therapy for type I diabetes: understanding the effects of glucose stimulation on islets in order to produce better islets for transplantation, Journal of Translational Medicine, doi: 10.1186/1479-5876-5-1. 39. Jiyeon Lee, Duck-Jong Han, Song-Che[r]

resistance may improve with weight reduction and drug treatment of hyperglycemia but itis seldom restored to normal.1.2Currently available Diabetes TreatmentsPatients with Type 1 Diabetes Mellitus (T1DM) are insulin dependent as a resultof autoimmune destruction of insulin producing beta cells