BÁO CÁO Y HỌC: "MUTAGENESIS OF THE TRANSMEMBRANE DOMAIN OF THE SARS CORONAVIRUS SPIKE GLYCOPROTEIN: REFINEMENT OF THE REQUIREMENTS FOR SARS CORONAVIRUS CELL ENTRY" PDF
Tìm thấy 10,000 tài liệu liên quan tới tiêu đề "Báo cáo y học: "Mutagenesis of the transmembrane domain of the SARS coronavirus spike glycoprotein:...":
BÁO CÁO Y HỌC: "MUTAGENESIS OF THE TRANSMEMBRANE DOMAIN OF THE SARS CORONAVIRUS SPIKE GLYCOPROTEIN: REFINEMENT OF THE REQUIREMENTS FOR SARS CORONAVIRUS CELL ENTRY" PDF
BioMed CentralPage 1 of 13(page number not for citation purposes)Virology JournalOpen AccessResearchMutagenesis of the transmembrane domain of the SARS coronavirus spike glycoprotein: refinement of the[r]
13 Đọc thêm
BÁO CÁO HÓA HỌC:" THE SARS CORONAVIRUS S GLYCOPROTEIN RECEPTOR BINDING DOMAIN: FINE MAPPING AND FUNCTIONAL CHARACTERIZATION" PPT
affect the binding to ACE2 are shown in red and those thatdo not affect the binding are in cyan. The two glycosyla-tion sites at 330 and 357 positions are colored in green. Inthe right panel the structure is rotated by 180° to show theopposite side of the RB[r]
10 Đọc thêm
BÁO CÁO KHOA HỌC PHOSPHORYLATION OF THE ARGININE SERINE DIPEPTIDE RICH MOTIF OF THE SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS NUCLEOCAPSID PROTEIN MODULATES ITS MULTIMERIZATION TRANSLATION INHIBITORY ACTIVITY AND CELLULAR LOCALIZATION PPTX
which functions to recruit cellular splicing factors forFig. 6. Overexpression of SRPK1 prevents N protein translocationto stress granules. HeLa cells were transiently cotransfected withvectors encoding FLAG-tagged full-length N, N-14A or NDRS andHA-tagged SRPK1, and treated with arsenite as[r]
12 Đọc thêm
BÁO CÁO SINH HỌC: " THE SARS CORONAVIRUS S GLYCOPROTEIN RECEPTOR BINDING DOMAIN: FINE MAPPING AND FUNCTIONAL CHARACTERIZATION" POT
Figure 5A shows the identified 13 amino acid residues,which can be mutated without affecting the function ofthe virus to cause infection. Interestingly, one of these res-idues, R426, which decreases binding to ACE2 about 10-fold if mutated to A, is mutated to G in one of[r]
10 Đọc thêm
BÁO CÁO SINH HỌC: " OLIGOMERIZATION OF THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) VPU PROTEIN – A GENETIC, BIOCHEMICAL AND BIOPHYSICAL ANALYSIS" PPT
Received: 4 July 2007Accepted: 29 August 2007This article is available from: http://www.virologyj.com/content/4/1/81© 2007 Hussain et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://c[r]
11 Đọc thêm
TÀI LIỆU BÁO CÁO KHOA HỌC: LAT – AN IMPORTANT RAFT-ASSOCIATED TRANSMEMBRANE ADAPTOR PROTEIN PPTX
important processes, such as antigen presentation, cellinteractions with pathogens and bacterial toxins, bud-ding of viruses from a host cell membrane, pathogene-sis of prion and other neurodegenerative diseases,specific forms of endocytosis, vesicle trafficking andestablis[r]
15 Đọc thêm
BÁO CÁO HÓA HỌC: " OLIGOMERIZATION OF THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (HIV-1) VPU PROTEIN – A GENETIC, BIOCHEMICAL AND BIOPHYSICAL ANALYSIS" PPTX
Vpu oligomerization based on gel electrophoretic and pull-down assays. The full-length R5-Vpu protein and its trans-membrane and cytoplasmic domains were synthesized and labeled with 35S-methionine in a coupled in vitro transcription-trans-lation system. (A) The proteins were analyzed[r]
11 Đọc thêm
BÁO CÁO KHOA HỌC: THE GXXXG MOTIF OF THE TRANSMEMBRANE DOMAIN OF SUBUNIT E IS INVOLVED IN THE DIMERIZATION/OLIGOMERIZATION OF THE YEAST ATP SYNTHASE COMPLEX IN THE MITOCHONDRIAL MEMBRANE DOC
chondrial membranes (Fig. 3).The e19A, eG15L and eG19L mutants are defectivein the mitochondrial morphologyIt has been previously reported that the null mutants ineither TIM11 or ATP20 genes have anomalous mitochon-drial morphologies [14,15]. Thus, transmission electronmicroscopy of[r]
10 Đọc thêm
O CÁO HÓA HỌC:" HIGH CHROMOSOME NUMBER IN HEMATOLOGICAL CANCER CELL LINES IS A NEGATIVE PREDICTOR OF RESPONSE TO THE INHIBITION OF AURORA B AND C BY GSK1070916" PPT
32. Gontarewicz A, Balabanov S, Keller G, Colombo R, Graziano A, Pesenti E,Benten D, Bokemeyer C, Fiedler W, Moll J, Brummendorf TH: Simultaneoustargeting of Aurora kinases and Bcr-Abl kinase by the small moleculeinhibitor PHA-739358 is effective against imatinib-resistant BCR-ABLmutat[r]
10 Đọc thêm
BÁO CÁO KHOA HỌC: IDENTIFYING DETERMINANTS OF NADPH SPECIFICITY IN BAEYER–VILLIGER MONOOXYGENASES DOCX
+compared with WT-HAPMO. The inactivity ofthis mutant suggests that NADPH could still bind to thismutant, but that the reduction of FAD or subsequent stepswere impaired, preventing turnover. The flavin-monitoredturnover data showed that R440A could indeed be fullyreduced by NADPH[r]
10 Đọc thêm
BÁO CÁO KHOA HỌC: MOLECULAR STRUCTURES AND FUNCTIONAL RELATIONSHIPS IN CLOSTRIDIAL NEUROTOXINS POTX
The interchain disulfide bond is also marked. (B) Ribbon representa-tion of BoNT ⁄ B. BoNT ⁄ A and BoNT ⁄ B are similar in fold anddomain organization. The three functional domains, receptor binding(BD), translocation (TD) and catalytic (CD) domains are representedin orange, gree[r]
19 Đọc thêm
BÁO CÁO SINH HỌC: " HIGH CHROMOSOME NUMBER IN HEMATOLOGICAL CANCER CELL LINES IS A NEGATIVE PREDICTOR OF RESPONSE TO THE INHIBITION OF AURORA B AND C BY GSK1070916" POTX
32. Gontarewicz A, Balabanov S, Keller G, Colombo R, Graziano A, Pesenti E,Benten D, Bokemeyer C, Fiedler W, Moll J, Brummendorf TH: Simultaneoustargeting of Aurora kinases and Bcr-Abl kinase by the small moleculeinhibitor PHA-739358 is effective against imatinib-resistant BCR-ABLmutat[r]
10 Đọc thêm
BÁO CÁO KHOA HỌC SECRETION OF THE MAMMALIAN SEC14P LIKE PHOSPHOINOSITIDE BINDING P45 PROTEIN PPTX
H + L) Ig and then with the TRITC- conjugated anti-HAmAb. After three washes with phosphate-buffered saline,cover slips with cells were mounted onto glass slides andviewed under a confocal laser scanning microscope (MRC-1024; Bio-Rad, Hercules, CA, USA) with a 60· oil immers-ion objective. A[r]
11 Đọc thêm
BÁO CÁO HÓA HỌC: " CUTANEOUS AND MUCOSAL HUMAN PAPILLOMAVIRUSES DIFFER IN NET SURFACE CHARGE, POTENTIAL IMPACT ON TROPISM" PPTX
assembly of papillomaviral vectors. J Virol 2004, 78(2):751-757.15. Pyeon D, Lambert PF, Ahlquist P: Production of infectious humanpapillomavirus independently of viral replication and epithe-lial cell differentiation. Proc Natl Acad Sci USA 2005,102(26):9311-9316.16. Buc[r]
6 Đọc thêm
BÁO CÁO KHOA HỌC: LOCALIZING MATRIX METALLOPROTEINASE ACTIVITIES IN THE PERICELLULAR ENVIRONMENT DOC
et al. [89] showed that MMP-9 secreted by activatedPMN leucocytes binds to the cell surface by anunknown mechanism. Significantly, the bound enzymeis fully functional proteolytically, although is no longerregulated by TIMP-1 or TIMP-2. Bannikov et al. [90]found that the gelatinol[r]
14 Đọc thêm
BÁO CÁO Y HỌC: " ROLE OF THE C-TERMINAL DOMAIN OF THE HIV-1 GLYCOPROTEIN IN CELL-TO-CELL VIRAL TRANSMISSION BETWEEN T LYMPHOCYTES" POTX
human immunodeficiency virus type 1-induced virological synapse formation between T cells. J Virol 2007, 81:13916-21.17. Jolly C, Sattentau QJ: Human immunodeficiency virus type 1 assembly, budding, and cell-cell spread in T cells take place in tetraspanin-enriched plasma membrane doma[r]
11 Đọc thêm
BÁO CÁO KHOA HỌC THE CAPSID PROTEIN OF HUMAN IMMUNODEFICIENCY VIRUS INTERACTIONS OF HIV 1 CAPSID WITH HOST PROTEIN FACTORS PPT
The exact role of CyPA in the viral lifecycle isunclear and remains a subject of intense debate [49–51]. The significance of this interaction is supported byan alignment of primate lentiviruses, which showedhigh conservation of the CyPA b[r]
10 Đọc thêm
BÁO CÁO KHOA HỌC IDENTIFICATION OF FUNCTIONAL DOMAINS IN THE FORMYL PEPTIDE RECEPTOR LIKE 1 FOR AGONIST INDUCED CELL CHEMOTAXIS DOC
DNA fragments between FPR and FPRL1 as previouslydescribed [12] to yield chimeras containing reciprocal seg-ments selected from these receptors. The restriction sitesAvaI (the first transmembrane domain, TM-1), NcoI (thefirst extracellular loop), and PvuII (TM-7) contained[r]
10 Đọc thêm
BÁO CÁO Y HỌC: THE SODIUM PUMP ITS MOLECULAR PROPERTIES AND MECHANICS OF ION TRANSPORT POTX
on the cytosolic side, and L1/2, L3/4, L5/6, L7/8, and L 9/10are accessible from the extracellular side.)First, the ATP phosphorylation site is localized withinthis loop as a part of the sequence DKTGT/S that is highlyconserved among all P-type ATPases. In addition[r]
10 Đọc thêm
ACKNOWLEDGEMENTS
My sincere thanks go to all lecturers and the staff of the Department of Post Graduate Studies at Hanoi College of Foreign Language for their useful materials, guidance and enthusiasm du[r]
1 Đọc thêm