16. Regelson W, Loria R, Kalimi M. Hormonal intervention: "buffer hormones" or "state dependency". The role of dehydroepian-drosterone (DHEA), thyroid hormone, estrogen and hypophy-sectomy in aging. Ann N Y Acad Sci. 1988; 521: 260-73. 17. Herbert J. Neurosteroids, brain damage, and mental illness.[r]
were measured at the beginning and end of the 30-day treatment phase. BMI was calculated as the body weight in kilograms divided by the square of the height in meters. Bodv Weight and Composition Body weights, performed on undressed indi-viduals, were measured using a calibrated Bodymas-ter S[r]
self-monitoring, engaging in healthy food choices and physical activity, and compliance with medications and doctor’s visits [24]. Subjects in this group received phone calls every other week and came to the HNRCA for testing at baseline and 16 weeks. We chose this approach rather than an attention-[r]
by all nucleated cells and is secreted into the blood at a constant rate [1, 2]. Cys-C is freely filtered through the normal glomerular membrane and completely reabsorbed, followed by catabolization by the proximal tubular cells [1, 2]. The biological fates of Cys-C are favorable as an endoge[r]
the intracellular pool to the plasma membrane [5, 6]. However, sustained insulin deficiency leads to a decreased number of GLUT4 transporters, resulting in impaired responsiveness of glucose transport to both insulin and exercise [4, 7]. People with type 2 diabetes have been shown to have def[r]
highly significant association between the rare C allele and lower plasma HDL concentrations in female subjects. The effect remained significant after correcting for multiparametric testing according to Bonferoni and was seen only in subjects with a BMI below the median. In addition, the non-[r]
which was established to characterize cognition among individuals initiating HAART for the first time as the country rapidly escalated access to antiretrovi-ral drugs. 2. METHODS Subjects and Clinical Data. We established a longitudinal neuroAIDS cohort within the Southeast Asia Research Coll[r]
which is the final irreversible stage characterized by parenchymal nodules with encircling fibrous septa. The hepatitis C virus is not considered to directly injure the liver but it rather triggers an HCV-specific lymphoproliferation. Through profuse cytokine production and also a direct cyto[r]
sity and is influenced by genetic and environmental factors, and in particular, changes in diet and physical activity [8,9]. Lipid abnormalities associated with obe-sity include increased overall production of lipids with elevated concentrations of fatty acids, triacyl-glycerols, and low-density lip[r]
antiviral therapy. 2. VIROLOGICAL TOOLS Serological assays Anti-HCV antibody detection The detection of anti-HCV antibodies in plasma or serum is based on the use of third-generation EIAs, that detect mixtures of antibodies directed against various HCV epitopes. Recombinant antigens are used to capt[r]
purchased from Charles River Laboratories Inc. (Wilmington, MA, USA). The culture medium was DMEM/F12 supplemented with 20% (vol/vol) Knockout (KO) serum replacement, 1mM L-glutamine, 1% nonessential amino acid, 100mM β-mercaptoethanol and 4ng/ml bFGF. All cell cultures were carried out on 6-well cu[r]
virus. In this study, HCVRNA was detected more frequently in patients with anti-HCV positive (90.7% of 130) than in patients with HBsAg/anti-HCV positive (65.2% of 69, p<0.001). 5. Antivirus Therapy Few data exist on treatment of double infection. Some preliminary studies [45,46] showed that[r]
As an example we presented the finding that maternal use of loratadine in early pregnancy was associated with a roughly doubled risk for infant hypospadias. We concluded: “The finding can still be random, but causality cannot be dismissed, even though the mechanism of action is not understood[r]