ADVANCES IN DIAGNOSIS OF IMPORTANT PROTOZOAN DISEASES: OLD AND NEW APPROACHES

2.5.3 RAS mutations
Three RAS genes, H-RAS, K-RAS, and N-RAS, synthesize a family of 21-kDa proteins that play an important role in tumorigenesis. Their function is to convey signals originating from tyrosine kinase membrane receptors to a cascade of mitogen-act[r]

Drug Combination is one of the effective approaches for treating complex diseases. However, determining combinative drug pairs in clinical trials is still costly. Thus, computational approaches are used to identify potential drug pairs in advance.

and techniques are mastered, the full characterization (titratlon and kinetic parameter determination) can be accomplished In less than a day.
The determinatlon of enzyme velocIty requires that experimental values be represented In[r]

The diagnosis of mitochondrial diseases is a real challenge because of the vast clinical and genetic heterogeneity. Classically, the clinical examination and genetic analysis must be completed by several biochemical assays to confirm the diagnosis of mitochondrial disease.

Despite recent advances in the diagnosis and treatment of breast cancer, metastasis remains the main cause of death. Since migration of tumor cells is considered a prerequisite for tumor cell invasion and metastasis, a pressing goal in tumor biology has been to elucidate factors regulating their mig[r]

Although there have been major advances in the treatment of unresectable metastatic colorectal cancer within the last 10 years, including the introduction of new cytotoxic and molecular [r]

of the target molecule. Nucleic acids can also be detected with sandwich assays. For example, the Liao group developed an electrochemical sensor assay to detect urinary pathogens in clinical samples based on immobilized capture oligonucleotide and labeled detector oligonucleotid[r]

Case presentation
A 14-year-old boy collapsed while playing a football match at school. Bystander CPR, including both chest compressions and mouth-to-mouth resuscitation, was immediately started by a witness who was trained in basic life support (BLS), while the emergency medi[r]

Tuberculosis is a major public health problem and second largest cause of death among infectious diseases. Rapid diagnosis of tuberculosis and detection of drug resistance is essential for effective disease control.

Since last few years, an impressive amount of data has been generated regarding the basic in vitro and in vivo biology of neural stem cells (NSCs) and there is much far hope for the success in cell replacement therapies for several human neurodegenerative diseases and stroke. The discovery of adult[r]

Date palm (Phoenix dactylifera L.) is an important fruit tree in north of Sudan and it was observed to be severely affected by many diseases. This study was carried out to evaluate the incidence and distribution of fungal diseases in date palm in its main producing areas in north of Sudan. A total o[r]

The survival rates of women with breast cancer have improved significantly over the last four decades due to advances in breast cancer early diagnosis and therapy. However, breast cancer survivors have an increased risk of cardiovascular complications following chemotherapy.

Recent advances have shown that histology and genetic biomarkers are important in patient selection, which have led to significantly better outcomes for lung cancer patients. However, most new treatments only apply to adenocarcinoma or non-squamous, and in squamous carcinoma there is little breakthr[r]

Pathogen detection in clinical samples based on 16S metagenomic sequencing technology in microbiology laboratories is an important strategy for clinical diagnosis, public health surveillance, and investigations of outbreaks.

The pathogenic fungi often cause huge impacts on agricultural crops, and occupy over 80% of plant diseases. Fusarium oxysporum and Rhizoctonia solani are fungal pathogens that can lead to rapid development of plant diseases on important crops in Tay Nguyen (e.g., pepper, coffee, rubber, cashew).

domains within the extracellular region, which are important for ligand binding, and result in nonsynonymous amino acid changes at residue 297V/I and 472H/Q, respectively. It is showed that patients carrying the KDR mutations are more susceptible to CHD. The higher CH[r]

Men have learnt to fill up their free time with TRANG 4 Science has both curse and blessing with various new diseases and cures.. Some of these diseases are different in that they affect[r]

Advances and innovations in nuclear decommissioning10 the end state of materials, buildings, and sites restricted or unrestricted release Advances and innovations in nuclear decommissioning10 the end state of materials, buildings, and sites restricted or unrestricted release Advances and innovat[r]