HIGH BLOOD GLUCOSE LEVELS ARE ASSOCIATED WITH HIGHER RISK OF COLON CANCER IN MEN: A COHORT STUDY

Physical activity is consistently associated with a reduced risk of colorectal cancer in epidemiologic studies. This association among higher risk subgroups, such as those with a first-degree family history of colorectal cancer or high body mass index remains unclear.

We have previously reported overexpression of the immunoregulatory protein B7-H3 in colorectal cancer and that nuclear expression predicted poor outcome in colon cancer patients. The present study was performed to examine the prognostic role of B7-H3 in an independent colorectal cancer cohort.

For the expanding population of bladder cancer survivors in Korea, the development of subsequent cancers is a significant concern. Here, we provide the second primary cancer incidence rates and types in Korean patients with bladder cancer.

Studies have shown that abnormal changes of specific-gene DNA methylation in leukocytes may be associated with an elevated risk of cancer. However, associations between the methylation of the zinc-related genes, WT1 and CA10, and breast cancer risk remain unknown.

in 1976, and has a 97% coverage, following validation against the records of the mandatory Swedish National Cancer Register.
Additional file 1: Figure S1 illustrates the cohort selection for this study. From the subgroup of 1824 women aged 20 years[r]

Report Date: June 19, 2007 Questions 1. Should primary care providers routinely perform total-body skin examination on members of the general population to screen for melanoma, basal cell carcinoma, and squamous cell carcinoma of the skin? 2. Should primary care providers routinely c[r]

A remarkable increase in the number of thyroid cancer cases has been reported in recent years; however, the markers to predict high-risk groups have not been fully established. This study demonstrated that the levels of biomarkers of thyroid function/autoimmunity, particularly the presence of TPOAb,[r]

Some triple negative breast cancer (TNBC) patients are at higher risk of recurrence in the first three years after treatment. This rapid relapse has been suggested to be associated with inflammatory mediators induced by radiation in healthy tissues that stimulate cancer cell migration and metastasis[r]

Metastasis of colorectal cancer (CRC) is directly linked to patient survival. We previously identified the novel gene Metastasis Associated in Colon Cancer 1 (MACC1) in CRC and demonstrated its importance as metastasis inducer and prognostic biomarker.

Study the Malondialdehyde content in patients with colon cancer who underwent radical surgery treatment. Evaluate the changes in red blood cell Malondialdehyde content of patients with colon cancer after radical surgery.

The transcription factor nuclear factor erythroid 2-related factor 2 (NFE2L2; previously known as NRF2) is a crucial regulator of the intracellular antioxidant response. It controls the expression of genes involved in the detoxification and elimination of reactive oxidants and electrophilic agents.

Antigen-processing machinery molecules play crucial roles in infectious diseases and cancers. Studies have shown that polymorphisms in endoplasmic reticulum aminopeptidase (ERAP) genes can influence the enzymatic activity of ERAP proteins and are associated with the risk of diseases.

Colorectal cancer is one of the major causes of cancer mortality world-wide. Prevention would improve if at-risk subjects could be identified. The aim of this study was to characterise plasma protein biomarkers associated with the risk of colorectal cancer in samples collected prospectively, before[r]

This study investigated whether patients with acquired haemolytic anaemia (AHA) would have elevated cancer risk including that for non-haematological solid tumours. We further examined whether the cancer risk would be different between patients with autoimmune type AHA (AIHA) and patients of non-AIH[r]

To investigate the association and magnitude of risk between JIA, its associated treatment and cancer development in Taiwanese children. Nationwide population-based 1:4 age- and gender-matched retrospective cohort study was designed using the National Health Insurance Research Database of Taiwan.

Healthiest Foods on Earth1 Berries All berries are low in sugar and high in fiber. Blueberries have been shown to increase memory in lab studies, and raspberries and strawberries are loaded with ellagic acid, a powerful antioxidant that seems t[r]

Examination of factors associated with late stage diagnosis of breast cancer is useful to identify areas which are amenable to intervention. This study analyses trends in cancer stage at diagnosis and impact of socio-demographic, cancer biological and screening characteristics on cancer stage in a p[r]

The role of post-mastectomy radiotherapy (PMRT) in the treatment of patients with T1–2N1 breast cancer is controversial. This study’s purpose was to evaluate the risk of recurrence of T1–2N1 breast cancer and the efficacy of PMRT in low-, medium- and high-risk groups of patients.

Acromegaly is a rare disease associated with an increased risk of developing cancer. Case presentation: We report the case of a 72-year-old man who was diagnosed with acromegaly (IGF-1 770 ng/ml) and breast cancer. Four years before he suffered from a colon-rectal cancer. Pituitary surgery and octre[r]

researchers throughout the nation, and the Public Health Insti-tute. It collects information about all cancers diagnosed in Cal-ifornia (except basal and squamous cell carcinoma of the skinand carcinoma in situ of the cervix). The database includesinformation on demograph[r]