INTERLEUKIN-8 IS NOT A PREDICTIVE BIOMARKER FOR THE DEVELOPMENT OF THE ACUTE PROMYELOCYTIC LEUKEMIA DIFFERENTIATION SYNDROME
Tìm thấy 10,000 tài liệu liên quan tới tiêu đề "Interleukin-8 is not a predictive biomarker for the development of the acute promyelocytic leukemia...":
Differentiation syndrome (DS) is the main life-threatening adverse event that occurs in acute promyelocytic leukemia (APL) patients treated with all-trans retinoic acid (ATRA). Cytokine imbalances have been reported to play role during the developing of acute promyelocytic leukemia differentiation s[r]
cancers.Genetic risk factorsInheritable single gene mutations that cause childhood cancers are rare.Retinoblastoma and Wilm’s tumors are two best known examples. Retinoblastomaoccurs when there are mutations that destroy both copies of the tumor suppressorretinoblastoma (Rb) gene. In <[r]
This meta-analysis was performed to explore the impact of minimal residual disease (MRD) prior to transplantation on the prognosis for patients with acute lymphoblastic leukemia (ALL).
port interactions may contribute to an increase in stress ornegative feelings.In extrapolating these findings, there are methodologicallimitations that need to be addressed. Specifically, withregard to the study design, the strategy used in selectingstudy participants, and the a[r]
the existence in environmental samples of chemicals with toxic properties, acting either singly or in combination. Some of them provide measures of the operation of certain modes of action, thus giving evidence of the types of com[r]
The simultaneous Occurrence of chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML) has been rarely reported. Most of these cases have been occurring more frequently as a secondary event in patients receiving chemotherapeutic agents for CLL.
Acute lymphocytic leukemia (ALL) is the most common pediatric cancer. The exact cause is not known in most cases, but past epidemiological research has suggested a number of potential risk factors. This study evaluated associations between environmental and parental factors and the risk for ALL in E[r]
8 to 10–6 M methotrexate in three to four doses. However, with decreased creatinine clearance, doses of 50–100 mg/m2 are continued until methotrexate levels are <5 x10–8 M. In addition to bone marrow suppression and mucosal irritation, methotrexate can cause renal failure[r]
USA [4]. Cases considered as 'possible' were excludedfrom all calculations, even though age distribution, sea-sonal trends and residence were similar to 'confirmed'cases. Although all causes were studied, mumps virus andthe California serogroup viruses were the most commonlyidentified causes[r]
Chapter 104. Acute and Chronic Myeloid Leukemia (Part 1) Harrison's Internal Medicine > Chapter 104. Acute and Chronic Myeloid Leukemia Acute and Chronic Myeloid Leukemia: Introduction The myeloid leukemias are a heterogeneous group [r]
Myeloid leukemia may be classified as Acute Myeloid Leukemia (AML) or Chronic Myeloid Leukemia (CML) based on its rate of progression. Administration of drugs is the best modality to treat myeloid leukemia, Imatinib mesylate (IM) and cytarabine (cyt) for CML and AML respectively. However, these drug[r]
17, 4680–4694.15 Luong MX, van der Meijden CM, Xing D, Hesselton R,Monuki ES, Jones SN, Lian JB, Stein JL, Stein GS,Neufeld EJ et al. (2002) Genetic ablation of theCDP ⁄ Cux protein C terminus results in hair cycle defectsand reduced male fertility. Mol Cell Biol 22, 1424–1437.16 Sinclair AM,[r]
Programmed cell death ligand 1 (PD-L1) is a potential predictive biomarker of the response to antiPD-L1/anti- programmed cell death 1 (PD-1) therapy in multiple cancers, including triple negative breast cancer(TNBC).
predictive model.Author Tran Quang Tuan (2012) has done modeling online adaptiveparameters based on estimate the fuzzy model parameter fornonlinear object, which has uncertain component, is a function. Thisdissertation does not study the optimization strateg[r]
Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) are myeloid neoplasms in which outgrowth of neoplastic clones disrupts normal hematopoiesis. Some patients with unexplained persistent cytopenias may not meet minimal diagnostic criteria for MDS but an alternate diagnosis is not appare[r]
ModelerWorkflowManagerExternalValidationPublication13425678Figure 1. Workflow diagram of the NCI Thésaurus editing and publication cycle. This is an abbreviated version of the editingworkflow process. The numbers in the figure correspond to the[r]
predominantly in neonates, immunocompromised patients (especially those with AIDS), and recipients of prolonged antibiotic or glucocorticoid therapy. In addition to sore throat, patients often report a burning tongue, and physical examination reveals friable white or gray plaques on
Acute myeloid leukemia (AML) is the second-most common form of leukemia in children. Aberrant DNA methylation patterns are a characteristic feature of AML. GATA4 has been suggested to be a tumor suppressor gene regulated by promoter hypermethylation in various types of human cancers although the exp[r]
NRG1 type III, independent of axon diameter, provides a key instructive sig-nal that determines the ensheathment fate of axons (Taveggia et al., 2005).Ensheathed axons express low levels whereas myelinated fibers express high levelsof NRG1 type III. Type III is t[r]
Total RNA was extracted from patient samples by using TRIzol reagent (Life Technologies, Grand Island, NY) according to the manufacturer’s protocol. The purity and integrity of total RNA were tested to assess the RNA quality. First, the OD ratios at A260/A280 and A[r]