Neoadjuvant therapy plus oesophagectomy has been accepted as the standard treatment for patients with potentially curable locally advanced oesophageal cancer. No completed randomized controlled trial (RCT) has directly compared neoadjuvant chemotherapy and neoadjuvant chemoradiation in patients with[r]
Neuroendocrine tumors (NETs) frequently overexpress somatostatin receptors (SSTRs), which is the molecular basis for 68Ga-DOTATOC positron-emission tomography (PET) and radiopeptide therapy (PRRT). However, SSTR expression fluctuates and can be subject to treatment-related changes.
Therapy targeted to the human epidermal growth factor receptor type 2 (HER2) is used in combination with cytotoxic therapy in treatment of HER2+ breast cancer. Trastuzumab, a monoclonal antibody that targets HER2, has been shown pre-clinically to induce vascular changes that can increase delivery of[r]
A major impediment in the treatment of ovarian cancer is the relapse of chemotherapy-resistant tumors, which occurs in approximately 25% of patients. A better understanding of the biological mechanisms underlying chemotherapy resistance will improve treatment efficacy through genetic testing and nov[r]
Ramucirumab monotherapy as a second-line treatment for advanced gastric cancer (AGC) prolongs survival compared to the best supportive care. However, in clinical practice, ramucirumab monotherapy is sometimes used as third- or later-line treatment for AGC refractory to fluoropyrimidine and taxanes.
Metabolic syndrome is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Insulin resistance, visceral adiposity, atherogenic dyslipidem[r]
This study aimed to investigate the efficacy and safety of cytokine-induced killer (CIK)/dendritic cell combined with CIK (DC–CIK) cell therapy in advanced gastrointestinal cancer (GIC).
Introduction to the Physics and T echnology of Extracorporeal Shock Wave Therapy (ESWTCSWT) STORZ MEDICAL AG, Kreuzlingen, Switzerland Kreuzlingen, October 2003 Physics and Technology of ESWTCSWT t Table of contents Definition of Shock Waves .......................................................[r]
... in the system Anaerobic Sequencing Batch Reactor for the Treatment of Municipal Wastewater Chapter Introduction Chapter 2.1 Literature Review Anaerobic process for wastewater treatment 2.1.1 Anaerobic. .. while the cost of anaerobic treatment is half of it (Lens and Verstraete, 15 Anaerobic Sequ[r]
The prognostic significance of TP53 concurrent mutations in patients with epidermal growth factor receptor (EGFR)- or anaplastic lymphoma kinase (ALK)- mutated advanced non–small-cell lung cancer (NSCLC) who received EGFR-tyrosine kinase inhibitors (TKIs) or ALK-TKIs based targeted therapy remains c[r]
Shockwave therapy in musculoskeletal treatmentMgr. Ondrej ProuzaPhysiotherapist BTL medical consultant Shockwave therapy Ondrej Prouza2Shockwave therapy contentsContents of presentation:Shockwave Therapy– physical principles technologyShockwave Therapy – medical backgroundShockwave Therapy clin[r]
1. Background: Lung cancer is one of the common cancers. The disease has the highest incidence and mortality among cancers, most commonly seen in the elderly especially over 60 years old. The majority of lung cancer is related to secondhand and passive smoking and has over[r]
Research and cancer care are closely intertwined; however, it is not clear whether physicians and nurses believe that clinical trials offer the best treatment for patients and, if so, whether this belief is justified.
(BQ) Part 2 book Nelson’s pediatric antimicrobial therapy presentation of content: Preferred therapy for specific parasitic pathogens, alphabetic listing of antimicrobials, antibiotic therapy for obese children, antibiotic therapy for patients with renal failure, adverse reactions to antimicrobial a[r]
Colon adenocarcinoma (COAD) is one of the most lethal cancers. It is particularly important to accurately predict prognosis and to provide individualized treatment. Several lines of evidence suggest that genetic factors and clinicopathological characteristics are related to cancer onset and progress[r]
In Brief: Influenza in 2015 Superseded by The Medical Letter "Influenza Vaccine for 2016-2017" - Issue 1505, October 10, 2016The CDC has announced that the most common influenza viruses circulating now are influenza A... Olodaterol (Striverdi Respimat) for COPD Olodaterol (Striverdi Respimat – Bo[r]
Dapagliflozin (Farxiga) for Type 2 Diabetes Dapagliflozin (dap" a gli fl oe'' zin; Farxiga – Bristol-Myers Squibb/AstraZeneca), an SGLT2 (sodium-glucose co-transporter 2) inhibitor, has been approved by the FDA for oral treatment... Macitentan (Opsumit) for Pulmonary Arterial Hypertension The FDA[r]