OF PROSTHETIC VASCULAR GRAFT INFECTIONS WITH THE USE OF ARTERIAL HOMOGRAFTS

Tìm thấy 10,000 tài liệu liên quan tới từ khóa "OF PROSTHETIC VASCULAR GRAFT INFECTIONS WITH THE USE OF ARTERIAL HOMOGRAFTS":

The medical letter on drugs and therapeutics august 18 2014

The medical letter on drugs and therapeutics august 18 2014

Two New Drugs for Skin and Skin Structure Infections The FDA has approved two new drugs for treatment of adults with acute bacterial skin and skin structure infections caused by susceptible gram-positive bacteria. Dalbavancin... Sucroferric Oxyhydroxide (Velphoro) for Hyperphosphatemia Most patients with end-stage renal disease develop hyperphosphatemia, which can lead to secondary hyperparathyroidism, vascular calcification, and cardiovascular mortality. The FDA has approved... Glycerol Phenylbutyrate (Ravicti) for Urea Cycle Disorders The FDA has approved an oral liquid formulation of glycerol phenylbutyrate (Ravicti – Hyperion) for chronic management of patients ≥2 years old with urea cycle disorders that cannot... A Transcutaneous Electrical Nerve Stimulation Device (Cefaly) for Migraine Prevention The FDA has approved the use of a transcutaneous electrical nerve stimulation device (Cefaly – Cefaly Technology) for prevention of episodic migraine in patients ≥18 years old. The...
Xem thêm

Đọc thêm

PROGRESS TEST

PROGRESS TEST

Progress test Unit 7 Test BName: ___________________________________________Grammar1 Complete the sentences. Use the past simple form of the verbs below.do win catch go read speak get1 My brother _______ a school chess competition last year.2 I _______ a lot of gifts for my last birthday.3 Last weekend we _______ to the cinema.4 We ________ a book by Jane Austen in our English literature class last week.5 The head teacher ________ to my parents about my poor grades yesterday.6 Colin ______ his maths homework late last night.7 We only ________ one fish in the lake at the weekend.Mark: ___ /72 Complete the sentences with the past simple form of the verbs in brackets. Use the affirmative,negative or interrogative forms.1 _______ (you / see) the football match last night?2 My parents _______ (go) shopping to buy some new clothes.3 We _______ (have) a great time on our holidays. The weather was hot every day.4 Sally _______ (cook) dinner yesterday. She went to the new restaurant in town instead.5 _______ (Dad / buy) a newspaper this morning?6 _______ (you / write) the party invitation to Suzie yesterday?7 Mark _______ (go) to the theatre because he was busy.Mark: ___ /73 Complete the text with the past simple form of the verbs below. Use the affirmative or negativeforms.have gobedo
Xem thêm

5 Đọc thêm

The medical letter on drugs and therapeutics march 27 2017

The medical letter on drugs and therapeutics march 27 2017

Bezlotoxumab (Zinplava) for Prevention of Recurrent Clostridium difficile Infection The FDA has approved the fully human monoclonal antibody bezlotoxumab (Zinplava – Merck) for use with antibacterial drug treatment to reduce recurrence of Clostridium difficile... Nusinersen (Spinraza) for Spinal Muscular Atrophy The FDA has approved nusinersen (Spinraza – Biogen) for treatment of spinal muscular atrophy (SMA), a hereditary neurodegenerative disease that occurs in about one in every 10,000... Exablate Neuro for Essential Tremor The FDA has approved use of Exablate Neuro (Insightec) for unilateral thalamotomy to treat medication-refractory essential tremor in patients ≥22 years old. Exablate Neuro uses... Obeticholic Acid (Ocaliva) for Primary Biliary Cholangitis Obeticholic acid (Ocaliva – Intercept), a farnesoid X receptor agonist, has been approved by the FDA for treatment of primary biliary cholangitis; it is indicated for use in combination... Triferic for Iron Replacement The FDA has approved ferric pyrophosphate citrate solution (Triferic – Rockwell Medical) to maintain hemoglobin concentrations in adults with hemodialysis-dependent chronic kidney... Inhibitors and Inducers of CYP Enzymes and P-glycoprotein (online only) View the Inhibitors and Inducers of CYP Enzymes and P-Glycoprotein table
Xem thêm

Đọc thêm

MANAGERIAL ECONOMICS STRATEGY BY M PERLOFF AND BRANDER CHAPTER 5 PRODUCTION

MANAGERIAL ECONOMICS STRATEGY BY M PERLOFF AND BRANDER CHAPTER 5 PRODUCTION

marginal product of labor is 13.– When the change in labor is very small (infinitesimal) weuse the calculus definition of the marginal product of labor:the partial derivative of the production function withrespect to labor [MPL = ∂q/∂L = ∂f(L,K)/∂L]5-7© 2014 Pearson Education, Inc. All rights reserved.5.2 Short-Run Production• Graphing the Product Curves– Figure 5.1 shows how output (total product), the average product of labor,and the marginal product of labor vary with the number of workers .• Product Curve Characteristics– In panel a, output rises with labor until it reaches its maximum of 110computers at 11 workers, point C.– In panel b, the average product of labor first rises and then falls as laborincreases. Also, the marginal product of labor first rises and then falls aslabor increases.– Average product may rise because of division of labor and specialization.Workers become more productive as we add more workers. Marginalproduct of labor goes up, and consequently average product goes up.– Average product falls as the number of workers exceeds 6. Workers mighthave to wait to use equipment or get in each other’s way because capitalis constant. Because marginal product of labor goes down, averageproduct goes down too.
Xem thêm

24 Đọc thêm

PUNCTUATION MARKS WITH INDEPENDENT CLAUSES

PUNCTUATION MARKS WITH INDEPENDENT CLAUSES

Punctuation marks with independent clausesIndependent clauses can be separated (or connected) in a variety of ways.Full stopWhen both clauses are of equal importance and can stand on their own, we usually use a full stop to separatethem.My toddler refuses to take a nap in the afternoon. He thinks he will miss out on some of the action.Here the two clauses are separated with a full stop because they express complete thoughts and can stand ontheir own.Comma + coordinating conjunctionSometimes we use a comma and a coordinating conjunction.My toddler refuses to take a nap in the afternoon, and I’m afraid that he will soon drive me crazy.Here the two independent clauses are connected with a conjunction and separated with a comma.By using a semicolonIn situations where you use a semicolon, you can use a full stop as well. The semicolon is preferred when theindependent clauses are too closely related.In spite of staying up all day, my toddler refuses to go to bed early; he thinks he will miss something.We can also use a transitional adverb to establish the connection between two independent clauses. Note that atransitional adverb (e.g. therefore, in addition, moreover, as a result etc.) does not connect the two clauses. Itmerely shows the flow of ideas.My toddler kept me awake all night; as a result, I don’t feel very well.Instead of the semicolon, we can use a full stop here.My toddler kept me up all night. As a result, I don’t feel very well.Don’t forget to put a comma after the transitional verb. Also note that a transitional adverb that follows asemicolon begins with a small letter.Stay on top of your writing! Download our grammar guide from www.englishgrammar.org to stay up-to-date.Powered by TCPDF (www.tcpdf.org)
Xem thêm

1 Đọc thêm

Teachers guide color vowel chart

TEACHERS GUIDE COLOR VOWEL CHART

The Color Vowel Chart is a pronunciation tool for teaching and learning English. When combined with the teaching techniques outlined here, the Chart provides an effective approach to teaching spoken English. The Chart will help you easily incorporate pronunciation into all of your classes so that your students can improve their comprehension and use of spoken English. This tool enables teachers and learners to talk easily and accurately about the key sounds of English without the use of phonetic symbols. Instead of phonetic symbols, the Chart uses colors and key words to represent the vowel sounds of English. This provides students and teachers with an easy way to describe and practice spoken English at the word level and at the phrase level.
Xem thêm

6 Đọc thêm

Thông khí nhân tạo và hô hấp ở trẻ em MECHANICAL VENTILATION IN THE NEONATE

Thông khí nhân tạo và hô hấp ở trẻ em MECHANICAL VENTILATION IN THE NEONATE

Supplemental Resources for the PICUNICU MECHANICAL VENTILATION IN THE NEONATE I. GENERAL PRINCIPLES A. NEONATAL VENTILATORS We use three types of neonatal ventilators in the NICU: 1. SIMV (Synchronized intermittent mandatory ventilation) 2. CPAP (Continuous positive airway pressure) 3. High Frequency Oscillatory Ventilator (HVOF) B. RESPIRATORY MINUTE VOLUME(Vm) 1. Tidal Volume (Vt ) is normally approximately 610 mLkg and 46 mlkg in the preterm. Respiratory rate (RR) is usually 3060 BPM. Tidal volume and respiratory rate are related to respiratory minute volume as follows: 2. The PaCO2level is inversely proportional to the minute volume. The higher the minute volume is, the lower the PaCO2will be. 3. During pressure ventilation, tidal volume (Vt) is proportional to PeakInspiratory Pressure (PIP) and to Dynamic Lung Compliance. 4. Respiratory minute volume can be altered by changing Ventilatory Rate or PIP (Vt ). C. OXYGENATION(PaO2) is directly proportional to: 1. Delivered oxygen (FiO2) 2. Mean airway pressure (MAP) II. PRESSURE VENTILATION A. DESCRIPTION The ventilator will rapidly reach the preset peak pressure limit and then hold the pressure for the remainder of the chosen inspiratory time. A pressure ventilator will deliver different tidal volumes with changes in lungcompliance and airway resistance. B. CONTROL 1. PEAK INSPIRATORY PRESSURE (PIP) High PIP is a major contributor to barotrauma in the lung. PIP is controlled and closely monitored. 2. INSPIRATORY TIME(It ) a. The normal newborn breathes with an I:E ratio of 1:1.5 to 1:2. Vm(mLmin) = Vtx RR This same ratio is used in infants with normal lung compliance and those with obstructive lung disease. b. A 1:1 I:E ratio is commonly employed for infants with impaired Dynamic Compliance in order to maximize alveolar recruitment. c. Mean airway pressure (MAP) is directly proportional to I:E ratio. Higher I:E ratios and MAP promote improved alveolar recruitment. d. At rates less than 40 BPM, inspiratory time is maintained at 0.3 0.6 sec. An attempt will normally be made to use the shortest It to minimize the MAP. e. It should be considered that different inspiratory times might have significant effects on tidal volume. Long inspiratory times may contribute to excessive alveolar distention in compliant lungs. 3. WAVEFORM a. A sine wave produces a slow gentle rise to peak pressure, useful in limiting barotrauma in infants with relatively normal compliance. b. A square wave produces a rapid risein airway pressure, useful in infants with poor lung compliance. c. Waveform will normally be adjusted by the respiratory therapist based upon the infants ventilatory requirements. 4. FLOW RATE a. Standard flow rates are 610 Lmin. Much of this flow is not delivered to the infant but rather is used to drive the ventilator. b. Infants on PIP greater than 20 cmH2O and rates in excess of 60 BPM may benefit from flow rates of 1216 Lmin in order to reach peak pressure more rapidly and deliver a larger tidal volume. This may be tested by using a pneumotachograph. C. MONITORING 1. The pressure ventilator automatically calculates and displays Rate and I:E. 2. PIP and PEEP and MAP are monitored by a Mean Airway Pressure monitor, which is far more accurate than an analog gauge. D. GENERAL PROCEDURE 1. Mechanical ventilation is initiated for respiratory failure and apnea. Hand bagging is a good way to test settings. 2. Inspiratory times are usually 0.3 0.6 second. 3. For RDS, I:E ratio should be 1:1. For obstructive lung diseases, use 1:1.5 or 1:2. 4. The Neonatal Respiratory Therapist will beresponsible for calculating and monitoring I:E changes that result from rate changes and informing the physician as needed. 5. A complete pressure ventilator order NEO RESP includes flow rate FiO2, rate, I:E ratio or It, PIP and PEEP. After initial settings, only changed parameters need to be ordered. Each morning, the complete current ventilator settings are clarified in NEO RESP. 6. Blood gas results are communicated to the physicianNNP by RT. A joint management decision is made and an order written. 7. It is very important that CLINICAL ASSESSMENT be performed after initiating respirator therapy. You should note: a. Color change, SaO2, HR, and RR b. Chest expansion c. Quality of breath sounds 8. The FELLOW OR ATTENDING NEONATOLOGIST is NOTIFIED of ANY SIGNIFICANT DETERIORATION. 9. Our preferred aim of management is to minimize MAP and FiO2. 10. Bedside tidal volume checks or pulmonary function tests are useful monitoring techniques. E. FOR ELEVATED PaCO2 1. Verify ET tube position and patency. Verify ABG. 2. Transilluminate, rule out pneumothorax, chest xray. 3. Increase rate in increments of 5 10 BPM. 4. Increase PIP in 2 cm H2O increments to achieve adequate chest expansion and tidal volume. 5. Decrease It in 0.1 sec increments until I:E = 1:1.5 6. Reduce PEEP if lungs are hyperventilated. 7. Increase rate further in 5 10 BPM increments as needed. 8. Consider muscle relaxation andor volume ventilation with fellowattending supervision. F. FOR REDUCED PaO2 1. Verify ET tube position and patency. Verify ABG. 2. Transilluminate, rule out pneumothorax, chest xray. 3. Increase FiO2up to 60%100%. 4. Increase It to 0.4 0.6 sec, I:E = 1:1. 5. Increase PEEP. 6. Increase PIP in 12cm H2O increments to deliver an optimal tidal volume. 7. Notify FellowAttending if no improvement. G. WEANING There are many ways of weaning from the respirator; the patients condition dictates the rate and method. Remember, changes are accomplished in small increments. (PIP 2 cm H2O, FiO25%, Rate 5 BPM). SaO2and TcPCO2monitoring are used to facilitate weaning. 1. Reduce FiO2to 80% before changing PIP, I:E or PEEP. 2. Reduce PIP as clinically indicated. 3. Reduce FiO2to less than 60% 4. Reduce It 5. Reduce PIP to 1014 cm H2O (Larger babies may be extubated with PIP 1418) 6. Reduce rate to 20 BPM H. DETERIORATION 1. Anytime the infant suddenly deteriorates: remove from ventilator, stabilize by hand ventilation with NRPR bag, and notify fellowattending. 2. Inadvertent extubation, malposition of ET tube (right mainstem), ET tube occlusion, must be quickly investigated. Auscultation, laryngoscopy, arterial blood gases and chest roentgenogram may be necessary. Emergency reintubation may be needed. 3. Pneumothorax may be diagnosed by auscultation, transillumination or chest xray. An emergency thoracentesis may be required. 4. Reset ventilator by stabilization settings used during hand ventilation. III. VOLUME VENTILATION A. DESCRIPTION 1. Volume ventilators deliver a preset tidal volume to the patient. The amount of pressure it takes to deliver that volume depends upon the airway resistance and the lung compliance of the patient. 2. Ventilator operates in eight possible modes of ventilation. The two modes we most commonly employ are: a. Volume control (vol) will be used in the acute, paralyzed patient. The volume control mode delivers regular mechanical breaths with a set Vt regardless of spontaneous breathing. b. Synchronized IMV (SIMV) with pressure support, used in the alert infant. SIMV guarantees a minimum minute volume while allowing the patient to trigger spontaneous breaths at a rate and volume determined by the patient. Extra breaths are boosted with pressure support. B. MONITORING 1. PIP and MAP are monitored by a transducer and displayed by the ventilator. 2. PEEP can be measured only by the analog gauge. C. INITIAL VOLUME VENTILATOR SETTINGS Two examples of expiratory Tidal Volume calculation follow: 1. A 3 kg infant requires a PIP of 40cm H2O: VE= 3 kg x 10 mLkg + (1.8 x 40)mL = 102 mL 2. A 3.6 kg postop cardiovascular surgery patient requiring 25cm H2O: VE= 3.6 kg x 15 mLkg + (1.8 x 25)mL = 99 Ml IV. HIGH FREQUENCY OSCILLATORY VENTILATION Definition HFOV is a method of mechanical ventilation that employs supraphysiological breathing rates and tidal volumes frequently less than dead space. Because conventional ventilation relies on the production of large pressure changes to induce mass flow of gas in and out of the lungs, it may be associated with deleterious consequences of volume and pressure changes at alveolar level. These include air leaks, such as PIE and pneumothorax, and bronchiolaralveolar injury leading to chronic lung disease. Indications Rescue: This is the most established role for HFOV Prophylactic: In animal experiments HFOV causes less lung injury than conventional ventilation. Principles of HFOV The use of high frequency ventilation at low tidal volumes allows the primary goals of ventilation, oxygenation and CO2 removal, to be achieved without the costs of pressureinduced lung injury. HFOV has been described as “CPAP with a wiggle”. This reflects the two physical goals: CPAP: Sustained inflation and recruitment of lung volume by the application of distending pressure (mean airway pressure MAP) to achieve oxygenation. Wiggle: Alveolarventilation and CO2removal by the imposition of an oscillating pressure waveform on the MAP at an adjustable frequency (Hz) and an adjustable amplitude (delta P). The ‘art’ of HFOV relates to achieving and maintaining optimal lung inflation. Optimal oxygenation is achieved by gradual increments in MAP to recruit lung volume and monitoring the effects on arterial oxygenation. The aim is to achieve maximum alveolar recruitment without causing overdistension of the lungs. Optimizing lung inflation with MAP: It is useful to conceptualize HFOV as like taking the lung around on sustained pressure volume hystersis loop. (Figure 2). Point A in figure: Underinflation: Atthis point, the lung is underinflated, PVR will be high and relatively large amplitude will produce only small changes in volume. Clinically, this manifests asa high oxygen requirement with limited chest vibration. Point B in figure: Optimal inflation:Once the lung has opened up with higher MAP, the PVR will fall and a smaller amplitude will produce a larger change in volume. Clinically, this manifests asfalling oxygen requirements and good chest vibration. Point C in figure: Overinflation: Again, more amplitude will be needed to produce volume changes and overinflated lung will compromise the systemic circulation. This is the most dangerous point in HFOV and is to be avoided at all costs It is difficult to pick up clinically because the oxygen requirement stays low, although they will eventuallyrise and the reduced chest vibration is easy to miss. Chest Xray iscurrently the best diagnostic tool for this. Point D in figure: Optimal inflation weaning: The goal should be to move the baby’s lungs from point B to point D avoiding point C. Having achieved optimal lung inflation by slowly reducing MAP, it should be possible to maintain the same lung inflation and ventilation at a low MAP. If MAP is lowered too far, oxygen requirements will start to rise. Optimizing the ventilation This is controlled by adjusting delta P to achieve optimal PCO2(4050 mmHg). Although the delta P of each breath appears large by comparison to conventional ventilation pressures, the attenuation of oscillation through the endotracheal tube means that the transmitted amplitude at the level of the alveolus is very small. Higherdelta P will increase tidal volume and hence CO2 removal. With increasing ventilator frequency, lung impedance and airway resistance increases so the tidal volume delivered to the alveoli decreases. This leads to the apparent paradox that increasing ventilator frequency may reduce CO2elimination, leading to raised PaCO2and viceversa. Practical Management Preparation: 1. If there is any significant leak around the ET tube, a larger one should be inserted. 2. Oxygen saturation, BP monitoring and arterial access should be used, if possible. 3. A preoscillation xray should be taken as a baseline. 4. Blood pressure and perfusion should be optimized prior to HFOV; any volume replacement contemplated should be completed and inotropes commenced, if necessary. 5. Muscle relaxants are not indicated unless previously in use. HFOV Adjustments Oxygenation and ventilation are best considered separately; however, adjusting the ventilator for one parameter will also alter other settings and so, after making a change, always check the other settings. 1) Ventilation: Changing the delta P or occasionally the frequency may effect changes in PaCO2. Raising the delta P of oscillation and vice versa may increase ventilation. Start at a delta P 12 cmH2O higher than conventional ventilation. Adjust the delta P in 12 increments until the chest wall is seen to “wiggle” down the point of the umbilicus. The optimal frequency of oscillation may be different in different disease states. Small infants with RDS may be managed at 15 Hz, term infants are often best managed at 10 Hz, although with very noncompliant stiff lungs, lower frequencies may be necessary. Note:If adjustment of frequency is needed, decreasing the frequency increases CO2 removal (opposite to CMV). 2) Adjusting the MAP and FiO2 controls oxygenation. The high lung volume strategy allows the use of low FiO2levels (
Xem thêm

Đọc thêm

co system generator

co system generator

Xilinx is disclosing this user guide, manual, release note, andor specification (the Documentation) to you solely for use inthe development of designs to operate with Xilinx hardware devices. You may not reproduce, distribute, republish, download, display, post, or transmit the Documentation in any form or by any means including, but not limited to, electronic, mechanical, photocopying, recording, or otherwise, without the prior written consent of Xilinx. Xilinx expressly disclaims any liability arising out of your use of the Documentation. Xilinx reserves the right, at its sole discretion, to change the Documentation without notice at any time. Xilinx assumes no obligation to correct any errors contained in the Documentation, or to advise you of any corrections or updates. Xilinx expressly disclaims any liability in connection with technical support or assistance that may be provided to you in connection with the Information.THE DOCUMENTATION IS DISCLOSED TO YOU “ASIS” WITH NO WARRANTY OF ANY KIND. XILINX MAKES NO OTHER WARRANTIES, WHETHER EXPRESS, IMPLIED, OR STATUTORY, REGARDING THE DOCUMENTATION, INCLUDING ANY WARRANTIES OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, OR NONINFRINGEMENT OF THIRDPARTY RIGHTS. IN NO EVENT WILL XILINX BE LIABLE FOR ANY CONSEQUENTIAL, INDIRECT, EXEMPLARY, SPECIAL, OR INCIDENTAL DAMAGES, INCLUDING ANY LOSS OF DATA OR LOST PROFITS, ARISING FROM YOUR USE OF THE DOCUMENTATION.© Copyright 2006 2011. Xilinx, Inc. XILINX, the Xilinx logo, Artix, ISE, Kintex, Spartan, Virtex, and other designated brandsincluded herein are trademarks of Xilinx in the United States and other countries. All other trademarks are the property of their respective owners.
Xem thêm

Đọc thêm

Clinico-mycological study of dermatophytoses at a tertiary care hospital in Belagavi, Karnataka, India

Clinico-mycological study of dermatophytoses at a tertiary care hospital in Belagavi, Karnataka, India

Dermatophytes are among the common fungal agents implicated in superficial skin infections worldwide. Infections commonly occur in hot and humid climates. They include species of Trichophyton, Microsporum and Epidermophyton. The present study was done to assess the clinical profile of dermatophytic infections and to identify the species of fungi that are prevalent in this region. A total of 80 samples consisting of skin scrapings, nail scrapings and hair follicles were collected from patients presenting with different ringworm/ tinea infections.

Đọc thêm

501 CRITICAL READING QUESTIONS P19

501 CRITICAL READING QUESTIONS P19

from the morning to the evening and then set back one hour inthe fall to return to normal daylight.Benjamin Franklin first conceived the idea of daylight saving duringhis tenure as an American delegate in Paris in 1784 and wroteabout it extensively in his essay, “An Economical Project.” It issaid that Franklin awoke early one morning and was surprised to seethe sunlight at such an hour. Always the economist, Franklinbelieved the practice of moving the time could save on the use ofcandlelight as candles were expensive at the time. In England,builder William Willett (1857–1915), became a strong supporterfor Daylight Saving Time upon noticing blinds of many houseswere closed on an early sunny morning. Willett believed everyone,including himself, would appre- ciate longer hours of light in theevenings. In 1909, Sir Robert Pearce introduced a bill in theHouse of Commons to make it obligatory to adjust the clocks. Abill was drafted and introduced into Parliament sev- eral times butmet with great opposition, mostly from farmers. Even- tually, in1925, it was decided that summer time should begin on the dayfollowing the third Saturday in April and close after the first Saturday in October.The United States Congress passed the Standard Time Act of1918 to establish standard time and preserve and set DaylightSaving Time across the continent. This act also devised five timezones throughout the United States: Eastern, Central, Mountain,Pacific, and Alaska. The first time zone was set on “the meanastronomical time of the seventy-185
Xem thêm

18 Đọc thêm

The medical letter on drugs and therapeutics january 5 2015

The medical letter on drugs and therapeutics january 5 2015

In Brief: Influenza in 2015 Superseded by The Medical Letter "Influenza Vaccine for 2016-2017" - Issue 1505, October 10, 2016The CDC has announced that the most common influenza viruses circulating now are influenza A... Olodaterol (Striverdi Respimat) for COPD Olodaterol (Striverdi Respimat – Boehringer Ingelheim), a new inhaled long-acting beta2-agonist, has been approved by the FDA for once-daily maintenance treatment of airflow... Oritavancin (Orbactiv) for Skin and Skin Structure Infections The FDA has approved oritavancin (Orbactiv – The Medicines Company), a long-acting lipoglycopeptide antibiotic given as a single intravenous (IV) dose, for treatment of acute bacterial... Trumenba: A Serogroup B Meningococcal Vaccine The FDA has approved Trumenba (Pfizer), a vaccine that protects against invasive meningococcal disease caused by Neisseria meningitidis serogroup B, for use in adolescents and young... Triumeq: A 3-Drug Combination for HIV The FDA has approved Triumeq (Viiv Healthcare), a fixed-dose combination of the integrase strand transfer inhibitor (INSTI) dolutegravir and the nucleoside reverse transcriptase inhibitors... Siltuximab (Sylvant) for Treatment of Multicentric Castleman''s Disease (online only) The FDA has approved the interleukin-6 (IL-6) antagonist siltuximab (Sylvant – Janssen), a recombinant chimeric (human-mouse) monoclonal antibody, for treatment of multicentric...
Xem thêm

Đọc thêm

746 SOMEANYAAN

746 SOMEANYAAN

WOULD YOU LIKE SOME ATEA?BOWL7-THISOF: SUGAR,RICE, SOUPIS ...........INTERESTINGBOOK. YOU SHOULDWE USE ANY WITH COUNTABLE OR UNCOUNTABLEREAD IT. NOUNS INQUESTIONS AND NEGATIVE SENTENCES.A CARTON OF: MILKEXAMPLE: IS THERE ANY MILK IN THE FRIDGE?THERE ISN’T ANY MILK INA THEFRIDGE.TIN OF:TUNAWE USE A WITH COUNTABLE NOUNS IN THE SINGULAR,OR BEFORECOMPLETE THE SENTENCES USING SOME OR ANYADJECTIVES THAT START WITH A CONSONANTA CUP OF: MILK, TEA, COFFEEEXAMPLE: A TOMATO1- THERE ISN’T .................WOOL TO GO ON KNITTING.A DIFFICULT LESSON2- ARE THERE ..............PENCILS FOR THE KIDS?WE USE AN WITH COUNTABLE NOUNS IN THE SINGULAR OR BEFORE3- THERE ARE ..............BUNS ON THE PLATE.ADJECTIVES THAT START WITH A VOWEL4- WOULD YOU LIKE ................ COFFEE?EXAMPLE: AN UMBRELLA5- I HAVE GOT .............. JAM IN THE FRIDGE IF YOU WANT.AN EASY EXAM
Xem thêm

1 Đọc thêm

predicate logic introduction

predicate logic introduction

Introduction Predicate logic builds heavily upon the ideas of proposition logic to provide a more powerful system for expression and reasoning. As we have already mentioned, a predicate is just a function with a range of two values, say false and true. We already use predicates routinely in programming, e.g. in conditional statements of the form if( p(...args ...) ) Here we are using the two possibilities for the return value of p, (true or false). We also use the propositional operators to combine predicates, such as in: if( p(....) ( q(....) || r(....) ) ) Predicate logic deals with the combination of predicates using the propositional operators we have already studied. It also adds one more interesting element, the quantifiers. The meaning of predicate logic expressions is suggested by the following:
Xem thêm

Đọc thêm

TO WHAT EXTENT DOES EXTENSIVE READING AFFECT THE L2 PROFICIENCY OF STUDENTS AT LOWER INTERMEDIATE LEVEL OF ENGLISH IN VINH PHUC HIGH SCHOOL FOR THE GIFTED

TO WHAT EXTENT DOES EXTENSIVE READING AFFECT THE L2 PROFICIENCY OF STUDENTS AT LOWER INTERMEDIATE LEVEL OF ENGLISH IN VINH PHUC HIGH SCHOOL FOR THE GIFTED

This is meant to reduce the feeling of obligation which may impede students’automaticity both during the whole programme and during their individualact of reading. Particularly, students should be encouraged discuss with theteacher to identify their own interest in reading, for instance, whether it isbooks about the environment/space or fiction books. For students in VinhPhuc senior secondary school for the gifted, this involvement is highlydesirable. From a psychological point of view, most of the students here,being teenagers, have very strong face-saving needs and the teacher’s failureto give them a sense of “ownership” of their reading project may causefeelings of compulsion and later dissatisfaction.b. Provide a wide range of textsIt is strongly believed that some variety in terms of genre and length of textscan minimize the student’s chance of feeling bored. For the success of anylengthy project, there should be abundant reading materials available in arange of genre and length. The teacher should note, however, that whatevertype of material, the language presented must be within the languagecompetence of the reader-student.c. Avoid the use of testsAs testing in our context is often associated with rote learning, memorizationand lack of freedom, extensive reading done at home or during an agreedperiod of time assigned should be totally detached from testing.d. Discourage the over-use of dictionaries88Dictionary use may harm the flow of the reader if she/he concentrates toomuch on looking up the meaning of every single new word. Pickard(1996:155) comments that, for the extensive reader-learner "Use of the
Xem thêm

22 Đọc thêm

Different associations of tumor PIK3CA mutations and clinical outcomes according to aspirin use among women with metastatic hormone receptor positive breast cancer

Different associations of tumor PIK3CA mutations and clinical outcomes according to aspirin use among women with metastatic hormone receptor positive breast cancer

The relationships among PIK3CA mutations, medication use and tumor progression remains poorly understood. Aspirin use post-diagnosis may modify components of the PI3K pathway, including AKT and mTOR, and has been associated with lower risk of breast cancer recurrence and mortality.

Đọc thêm

49243 QUANTIFIERS 1

49243 QUANTIFIERS 1

SOMEANY MUCH MANY A LOT (A) FEW(A) LITTLEWe use much and many mostly in question and negative. Much is used with uncountable nouns, and many is usedwith countable plural nouns.Ex: - Is there much rice left?- We haven’t got much rice left.- Has he got many books?- He hasn’t got many books.Note: We often use much and many in affirmative sentences after too, as, so and very.Ex: - Take as much milk as you want.- I’ve got so many jobs to do today.- We enjoy the party very much.- We’ve got too much milk.In affirmative sentences, we normally use a lot (of), lots (of) and plenty (of), not much and many.We use a lot (of), lots (of) and plenty (of) with both uncountable nouns and plural nouns.Ex: - We’ve got a lot of milk.(Not: We’ve got much milk.)- He’s got a lot of / plenty of books.(Not normally: He’s got many books.)BWe use a little to express positive idea with uncountable nouns. It means “a small amount, but some”.Ex: - There is still a little work to do.- I have a little sugar in the jar.We use a few to express positive idea with plural nouns. It means a small number, but some”.Ex: - A few students passed it because theexam is extremely difficult.
Xem thêm

3 Đọc thêm

MEDICAL MANAGEMENT OF VASCULAR ANOMALIES | WEBSITE BỆNH VIỆN NHI ĐỒNG 2 - WWW.BENHVIENNHI.ORG.VN

MEDICAL MANAGEMENT OF VASCULAR ANOMALIES | WEBSITE BỆNH VIỆN NHI ĐỒNG 2 - WWW.BENHVIENNHI.ORG.VN

• Patient 6: Bony LesionsBefore sirolimus therapy16 months on sirolimus therapyRESULTS• Patient 2RESULTS• Average length of initial treatment: 21months (range 2‐31‐ months)• Average length of follow up: 43 months(range 28 ‐59 months)• Five of six patients have requiredadditional treatment: 4 are currently onlow‐dose sirolimus (once daily) and one ofthese is starting to taperCONCLUSIONS• Sirolimus is an effective medication for lifethreatening vascular anomalies with goodresponses and limited side effects• Patients have had no long term ordevelopmental issues observed to date• Patients with symptoms of recurrence electedto be restart sirolimus for improvement in
Xem thêm

24 Đọc thêm

APPLICATION OF BIOCOMPATIBLE THIN ORGANIC COATINGS TO IMPROVE TRIBOLOGY OF TI6AL4V ALLOY

APPLICATION OF BIOCOMPATIBLE THIN ORGANIC COATINGS TO IMPROVE TRIBOLOGY OF TI6AL4V ALLOY

.. .APPLICATION OF BIOCOMPATIBLE THIN ORGANIC COATINGS TO IMPROVE TRIBOLOGY OF TI6AL4V ALLOY BHARAT PANJWANI (B.Tech, IIT Kanpur, India) A THESIS SUBMITTED FOR THE DEGREE OF MASTER OF ENGINEERING... and its alloys In this thesis, application of thin organic coatings to improve tribology of titanium and its alloys has been explored with emphasis on biomedical applications Ti6Al4V alloy, a... tribological limitations of Ti6Al4V alloy In this study, following approaches have been used:  Use of PFPE to improve the tribological properties of Ti6Al4V alloy  Use of PFPE overcoat to improve the tribological
Xem thêm

128 Đọc thêm

2D optical trapping potential for the confinement of heteronuclear molecules 4

2D OPTICAL TRAPPING POTENTIAL FOR THE CONFINEMENT OF HETERONUCLEAR MOLECULES 4

... is mm the aperture from other optical elements in the beam path 41 Figure 4. 17: Cut across the X axis of the output profiles of the beam shaped with the Error Diffusion Algorithm, and the RMS... y) = 34 (4. 3.6) We note the use of convolution theorem in the second line of the above equation We assume the pinhole to be spherical with an opening radius rph The Fourier Transform of the pinhole... spatial filter The plot of the convolution kernel (the Airy function) in figure 4. 7 shows that the typical size of the neighborhood which contributes to the output field is of the order of the first
Xem thêm

18 Đọc thêm

Applied TPB model to study the intention of returning tourists in Jinju, South Korea

Applied TPB model to study the intention of returning tourists in Jinju, South Korea

Applied TPB model to study the intention of returning tourists in Jinju, South KoreaRelying on the theory of planned behavior (Ajzen, 1991), a longitudinal study investigated the effects of an intervention—introduction of a prepaid bus ticket—on increased bus use among college students. In this context, the logic of the proposition that past behavior is the best predictor of later behavior was also examined. The intervention was found to influence attitudes toward bus use, subjective norms, and perceptions of behavioral control and, consistent with the theory, to affect intentions and behavior in the desired direction. Furthermore, the theory afforded accurate prediction of intention and behavior both before and after the intervention.
Xem thêm

Đọc thêm

Cùng chủ đề